Because of rapid advances in genome sequencing technology, we can finally see the source code for life: the complete genomic DNA sequences that specify development, regulation, and function of organisms. Our laboratory develops computational methods for genome sequence analysis. We are particularly interested in methods for identifying remote evolutionary relationships between distantly related protein and RNA sequences.
We're a Howard Hughes Medical Institute laboratory at Harvard University, in Molecular & Cellular Biology and in Applied Mathematics in Biolabs on the Cambridge campus. We're affiliated with the Harvard Data Science Initiative, the 安卓番羽土啬软件, and the Center for Brain Science.
If you're interested in doing a postdoc with us, contact me and propose a project idea. We usually have space and initial funding available.
Graduate students in the group come from many different Harvard programs, including MCO (Molecules, Cells, and Organisms), Systems Biology, Biophysics, Lantern专业版apk, and Physics.
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The Rfam database of RNA alignments, consensus secondary structures, and profile SCFGs.
The Dfam database of repetitive DNA sequence elements.